Endocrine Abstracts

Introduction: A biochemical profile of an underactive pituitary gland allied to visual field loss is commonly due to an underlying adenoma. We report a case where such a clinical picture was found but imaging/biopsy revealed a different cause.Case report: A 52-year-old Indian male was referred by his GP to an endocrine outpatient department with reduced visual acuity, balance problems and a biochemical profile of an underactive pituitary gland. Past hist...

Introduction: Cyclophosphamide is known to cause gonadal dysfunction. Specifically, it has been reported to cause damage to the seminiferous tubules causing raised FSH>LH with low testosterone levels. We present the case of a gentleman with raised FSH and LH following treatment with R-CHOP therapy. Interestingly, the testosterone level was high, signifying adequate physiological response.Case history: A 63-year-old gentleman was referred to endocrine...

Primary hyperparathyroidism (PHPT) is not uncommon. It has varied presentations ranging from asymptomatic disease to the classical ‘stones, groans, and moans’. The incidence and prevalence of frank diabetes mellitus (DM) is significantly increased in patients with hypercalcaemia. It may be difficult to differentiate symptoms of hypercalcaemia from DM. We present a case of improved glycaemia in a patient with DM following removal of parathyroid adenoma.<p class="a...

Background: Recent therapeutic advances have resulted in prolonged survival of thalassemia major patients reaching adulthood and attaining reproductive capacity. However, endocrine complications are commoner in thalassemia major patients with up to 30% of patients showing hypogonadotrophic hypogonadism. Although spontaneous pregnancy have been described in well chelated and transfused patients, majority of thalassemia major patients are infertile and need assisted reproductive...

Hypocalcaemia is a common presentation to the emergency department; patient’s symptoms vary but typically report pins and needles and muscle cramps, due to neuromuscular irritability. Other important features include ECG changes (prolonged QTc) and seizures. The most common causes are hypoparathyroidism, vitamin D deficiency and chronic kidney disease.A 25-year old male presented with symptomatic hypocalcaemia who was referred to us for follow up, a...